Elgg
A sample Elgg-1.8 configuration (Github Gist.)
I found this on the elgg forums. It looks like it could be improved if someone wants to test it.
server { server_name domain.com; rewrite ^/(.*) http://www.domain.com/$1 permanent; } server { server_name www.domain.com; client_max_body_size 8M; client_body_buffer_size 256k; location / { if ($request_method = POST) { proxy_pass http://localhost:8000; break; } default_type "text/html; charset=utf-8"; set $memcached_key "/budokin-$uri"; memcached_pass 127.0.0.1:11211; error_page 404 502 = /fallback; } location = /fallback { proxy_pass http://127.0.0.1:8000; break; } access_log off; #access_log /home/kam/www/budokin.com/log/access.log; error_log /home/kam/www/budokin.com/log/error.log; } server { listen 8000; server_name www.domain.com; root /home/user/domain.com; index index.php; client_max_body_size 8M; client_body_buffer_size 256k; location / { if (!-e $request_filename) { rewrite ^/action/([A-Za-z\_\-\/] +) /engine/handlers/action_handler.php?action=$1 last; rewrite ^/actions/([A-Za-z\_\-\/] +) /engine/handlers/action_handler.php?action=$1 last; rewrite ^/export/([A-Za-z] +)/([0-9] +) /services/export/handler.php?view=$1&guid=$2 last; rewrite ^/export/([A-Za-z] +)/([0-9] +)/([A-Za-z] +)/([A-Za-z0-9\_] +) /services/export/handler.php?view=$1&guid=$2&type=$3&idname=$4 last; rewrite ^/_css/css.css /_css/css.php last; rewrite ^/pg/([A-Za-z\_\-] +)/(.*) /engine/handlers/pagehandler.php?handler=$1&page=$2 last; rewrite ^/pg/([A-Za-z\_\-] +) /engine/handlers/pagehandler.php?handler=$1 last; rewrite ^/xml-rpc.php /engine/handlers/xml-rpc_handler.php last; rewrite ^/mt/mt-xmlrpc.cgi /engine/handlers/xml-rpc_handler.php last; } } location ~ \.php$ { fastcgi_connect_timeout 60; fastcgi_send_timeout 180; fastcgi_read_timeout 180; fastcgi_buffer_size 128k; fastcgi_buffers 4 256k; fastcgi_busy_buffers_size 256k; fastcgi_temp_file_write_size 256k; fastcgi_intercept_errors on; fastcgi_pass 127.0.0.1:9000; fastcgi_index index.php; fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name; fastcgi_param QUERY_STRING $query_string; fastcgi_param REQUEST_METHOD $request_method; fastcgi_param CONTENT_TYPE $content_type; fastcgi_param CONTENT_LENGTH $content_length; expires max; } access_log off; #access_log /home/kam/www/budokin.com/log/access.log; error_log /home/kam/www/budokin.com/log/error.log; #error_page 500 502 503 504 /50x.html; #location = /500.html { root /home/kam/www/nginx-default; } }